https://forums.phoenixrising.me/threads/pain-gone-with-ambroxol.62011/page-2

Pain gone with AMBROXOL

    Thread starter pattismith Start date Oct 25, 2018 

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pattismith
pattismith
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@Moof, did you have any sleepyness from it? this was a terrible side effect on
me, together with the weakness.

Ambroxol also have the potency of inhibiting microglial activation, so I will
try to keep it only at night to reduce the problem of the side effects I got.

Ambroxol is not only a neuroprotector but also a lung protector, which I need
too, so this is another reason why I wish to keep it.
 
Last edited: Nov 1, 2018
Nov 1, 2018
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Moof
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pattismith said:
@Moof, did you have any sleepyness from it? this was a terrible side effect on
me, together with the weakness.
Not in any significant way – I mostly felt my muscle fibres gradually starting
to relax about half an hour after I took it. Same thing happened again today.

If I can buy it over the counter here, I'll keep some in the cupboard for when
that symptom is particularly troublesome, or when I can't sleep because there's
pressure on my bladder all the time. Both happen when I've overdone it a bit,
and as I never really know where my limit is on any given day, it's all too easy
to do!

EDIT: What dose did you take? My mate's tablets are 30mg.
 
Nov 1, 2018
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pattismith
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Moof said:
Not in any significant way – I mostly felt my muscle fibres gradually starting
to relax about half an hour after I took it. Same thing happened again today.

If I can buy it over the counter here, I'll keep some in the cupboard for when
that symptom is particularly troublesome, or when I can't sleep because there's
pressure on my bladder all the time. Both happen when I've overdone it a bit,
and as I never really know where my limit is on any given day, it's all too easy
to do!

EDIT: What dose did you take? My mate's tablets are 30mg.
The tablets I have are 30 mg. I took 30 mg, but 15 mg does the job either. It
took about 1h30 for me to notice an effect.
 
Nov 1, 2018
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Moof
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Interesting, thank you – next time I need some, I'll try half a tablet and see
if works well enough. Always like to take the smallest dose I can!

I hope you can get around the sleepiness problem. I read some research about use
in fibromyalgia, which suggested the drug might become more effective if taken
long term, possibly allowing further dose reduction...you may also be able to
get beyond the sleepiness once your body's used to it.
 
Nov 1, 2018
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MEKoan
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Can someone tell me where to get Ambroxol? I'm in Canada, and it seems to be
impossible to get this side of the pond although not a restricted substance. I
have found a Canadian supplier but they only supply to research scientists, not
even to compounding pharmacies. I would be most interested in a form (pure
powder, maybe) that could be made into a cream.

I would be very grateful for any ideas.
 
Feb 14, 2019
Moof
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I bought it from the same German pharmacy as my B12 ampoules:

https://www.versandapo.de/ambroxol-30-tab-1a-pharma-100stk-pzn-03201957

Not easy to see form the UK whether they ship to Canada, but worth trying?

EDIT:

You can also get it as a liquid:

https://www.versandapo.de/ambroxol-15-saft-1a-pharma-100ml-pzn-03201319
 
Feb 14, 2019
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Thank you much, Moof! That is a great help!
 
Feb 14, 2019
Lisa108
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Unfortunately versandapo (and all other German online pharmacies I looked up so
far) don't ship 'abroad'. Europe only.
Edit: Europe and European Economic Area only.
Edit: Wait. I found one. But shipping is 69,95 €! Link here.
 
Last edited: Feb 14, 2019
Feb 14, 2019
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MEKoan
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Lisa 108, Big, big thanks to you for that fantastic search! I will follow that
link and see where it leads me. You have helped so much :0)

Has anyone discussed having a cream compounded? Recent studies indicate
excellent effect from topical use but there is no commercial cream. For
trans-dermal effect, it's unlikely to be as easy as crushing up tablets and
applying to skin, I imagine it matters a great deal what the filler in the
tablet is, for instance.

I have spoken to a compounding pharmacy here in Canada to see if they could
compound it, but their suppliers don't carry it. I spoke to a Canadian company
that supplies it, but only to research scientists, not the public or to
pharmacies. Not because it is regulated in any way, simply because they don't,
that's all.

Are there any discussions about this on the forum?

Thanks again, all :0)
 
Feb 14, 2019
Lisa108
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MEKoan said:
Lisa 108, Big, big thanks to you for that fantastic search! I will follow that
link and see where it leads me. You have helped so much :0)
You're welcome! The shipping fees are ridiculously high as the ambroxol is
really cheap here. Maybe someone could send it to you from the US?
 
Feb 14, 2019
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Iritu1021
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MEKoan said:
Can someone tell me where to get Ambroxol? I'm in Canada, and it seems to be
impossible to get this side of the pond although not a restricted substance. I
have found a Canadian supplier but they only supply to research scientists, not
even to compounding pharmacies. I would be most interested in a form (pure
powder, maybe) that could be made into a cream.

I would be very grateful for any ideas.
Mimaki Family pharmacy sells it.
 
Feb 14, 2019
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MEKoan
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Lisa108 said:
You're welcome! The shipping fees are ridiculously high as the ambroxol is
really cheap here. Maybe someone could send it to you from the US?
I thought it wasn't available in the US? Is it? That would be so much easier!
 
Feb 14, 2019
MEKoan
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Iritu1021 said:
Mimaki Family pharmacy sells it.
Thanks so much! :0)
 
Feb 14, 2019
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Lisa108
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MEKoan said:
I thought it wasn't available in the US? Is it? That would be so much easier!
Ah, sorry, totally overread this (and of course you'd have checked this before
trying exotic places...) I'd better stop here...:zippit:
 
Feb 14, 2019
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Lisa108
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MEKoan said:
Has anyone discussed having a cream compounded? Recent studies indicate
excellent effect from topical use but there is no commercial cream. For
trans-dermal effect, it's unlikely to be as easy as crushing up tablets and
applying to skin, I imagine it matters a great deal what the filler in the
tablet is, for instance.
This is the recipe that German pharmacies use (for off-label use and on request
only):

" 50,0 g cream contain

    Ambroxol 10,0 g (20%)
    Dimethylsulfoxid 5,0 g (10%)
    Linola®-cream ad 50,0 g"

The dimethylsulfoxid (DMSO) seems to be helping to dissolve the ambroxol, is
anti-inflammatory, decongestant and helps the ambroxol to penetrate the skin.

But now, back to :zippit:
 
Feb 14, 2019
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MEKoan
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Lisa, Yes, yes! Do you know of a pharmacy that will compound this? Please,
please unzip :0)
 
Feb 15, 2019
Lisa108
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MEKoan said:
Lisa, Yes, yes! Do you know of a pharmacy that will compound this?
I think that any German pharmacy can compound this. But the cream has only a
shelf-life of 4 weeks and has to be stored in the fridge... so this could be a
problem with shipping. And as I said, shipping fees from Germany to Canada are
very high.
 
Feb 15, 2019
Lisa108
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This pharmacy-chain says that they are shipping worldwide. Since they are
located at German airports, the shipping fees might be less. Maybe worth
contacting?

I don't know if they would compound a cream. But maybe they can ship ambroxol
hcl powder to a Canadian compounding pharmacy? At least they should know about
legal restrictions.

This German manufacturer is producing ambroxol hcl powder. I found one German
pharmacy offering the 25g pack size. (contact info here).
 
Feb 16, 2019
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MEKoan
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Lisa! What an amazing resource and researcher you are! I am astonished! And so
grateful to you!

And what a good idea re hooking up compounding pharmacies! You have been such an
amazing help! I can't stop using !!!

Thank you so much!
 
Feb 16, 2019
MEKoan
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There shouldn't be any legal restrictions beyond what there would be for
aspirin. It's not a controlled substance anywhere. Again: thank you!
 
Feb 16, 2019
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